Személyi adatok
Született: 1931. december 3., Kristyor, Románia
Családi állapota: nős
Munkahely:
Eötvös Loránd Tudományegyetem
Szerves Kémiai Tanszék
H-1518 Budapest 112
Pf. 32
telefon: 209-0555, mellék: 1410
fax: 372-2620
e-mail: afurka@szerves.chem.elte.hu
honlap: http://szerves.chem.elte.hu/Furka/
Iskolai végzettség és tudományos fokozatok:
1971 a kémiai tudomány doktora
1963 a kémiai tudomány kandidátusa
1959 egyetemi doktori fokozat, Szegedi Tudományegyetem
1959 vegyészdiploma, Szegedi Tudományegyetem
1955 kémia-fizika szakos középiskolai tanár, Szegedi Tudományegyetem
Munkahelyek:
1972- egyetemi tanár, Eötvös Loránd Tudományegyetem, Szerves Kémiai Tanszék
1995-99 tudományos tanácsadó, Advanced ChemTech Inc., Louisville, KY, USA
1966-72 egyetemi docens, Eötvös Loránd Tudományegyetem, Szerves Kémiai Tanszék
1961-66 tudományos munkatárs, MTA Peptidkémiai Kutatócsoport, közben 1964-1965 posztdoktori ösztöndíjas, University of Alberta, Department of Biochemistry, Edmonton, Canada
1956-61 egyetemi tanársegéd, Szegedi Tudományegyetem, Alkalmazott Kémiai Tanszék
1955-1956 középiskolai tanár, Makói Általános Gimnázium
Tagság tudományos szervezetekben:
Magyar Kémikusok Egyesülete
American Chemical Society
Magyar Biokémiai Társaság
European Peptide Society
American Association for the Advancement of Science
MKE Kombinatorikus Kémiai Szakcsoportja
European Society of Combinatorial Sciences
Szerkesztőbizottsági tagságok:
Molecular Diversity
Solid-Phase Organic Syntheses sorozat
Díjak, kitüntetések:
2002 Széchenyi-díj
2001 Tiszteletbeli Elnök, European Society of Combinatorial Sciences
1999 MTA Akadémiai Díj
1996 A Moet Henessy, Louis Vuitton cég "Vinci of Excellence" nemzetközi díja
1964 A National Research Council of Canada ösztöndíja
Furka Á.: Egy természetes g-glutamil-peptid izolálása és szintézise, In: Kémiai Közlemények, Vol. 58, 1982: 373-378.
Furka Á., Sebestyén F.: Egy rendkívüli hatékonyságú új módszer biooligomerek szintézisére, Magyar Kémikusok Lapja, Vol. 50, 1995: 3-6.
Furka Á.: Kombinatorikus kémia, In: MTA Közgyűlési Előadások, 1999: 559-571.
Furka Á.: A kombinatorikus kémia, In: Természet Világa, Vol. 131, 2000: 265-269.
Furka Á.: Visszapillantás a kombinatorikus kémia kialakulásának korai időszakára, In: Magyar Kémikusok Lapja, Vol. 56, 2001: 250-254.
Furka Á.: Hogyan született a zsinórszintézis?, In: Magyar Kémikusok Lapja, Vol. 58, 2003: 5-10.
G. Fodor, E. Fodor-Varga, Á. Furka: A kinetic contribution to the knowledge of carbon-rings, In: Croatica. Chem. Acta, Vol. 29, 1957: 303.
Á. Furka: Kinetical data to acyl migration N-O, In: Acta Phys. et Chem. Szeged, Vol. 5, 1959: 59.
Gy. Sipos, Á. Furka, T Szell: Kinetische Untersuchung der basenkatalysierten Chalkonbildung, In: Monatshefte für Chemie, Vol. 91, 1960: 643.
T. Szell, Á. Furka: A new method for working up processing mixtures containing anhydrous aluminium chloride, In: Nature, Vol. 184, 1959: 117.
T. Szell, Á. Furka: Isolation of 2-nitro-phenol from the mixture of mono-nitropphenols, In: Nature, Vol. 181, 1958: 481.
T. Szell, Á. Furka, I. Szilagyi: Conductivity of phenolic esters in nitrobenzene solutions containing alumunium chloride, In: Naturwiss., Vol. 46, 1959: 490
T. Szell, Á. Furka, I. Szilagyi: Fries rearrangement of some nitrophenolic esters, In: J. Sci. Ind. Res., India, Vol. 18B, 1959: 325.
T. Szell, Á. Furka, I. Szilagyi: Studies on the Fries rearrangement of phenolic esters, In: J. Sci. Ind. Res., India, Vol. 18B, 1959: 323.
Á. Furka, T. Szell: Study on Fries reaction. Part I. Isomerisation of thymyl acetate, In: J. Chem. Soc., 1960: 2312.
T. Szell, Á. Furka: Study on the Fries reaction. Part II. Effect of hydrogen chloride on the isomerisation of thymyl acetate, In: J. Chem. Soc., 1960: 2321.
Á. Furka, T. Szell: New method for the quantitative determination of esters in the presence of aluminium chloride, In: Acta Phys. et Chem. Szeged, Vol. 5, 1959: 66.
Á. Furka, T. Szell: Fries rearrangement of mononitrophenyl benzoates, In: Acta Phys. et Chem. Szeged, Vol. 6, 1960: 113.
Á. Furka, T. Szell: Fries rearrangement of some nitrophenolic esters in the absence of solvent, In: Acta Phys. et Chem. Szeged, Vol. 6, 1959: 122.
Á. Furka, T. Szell: Fries rearrangement of 3-nitro-phenyl benzoate, In: Acta Phys. et Chem. Szeged, Vol. 7, 1961: 70.
Á. Furka, T. Szell: Decomposition of mononitrophenolic esters in the presence of alumunium chloride, In: Acta Phys. et Chem. Szeged, Vol. 6, 1960: 116.
Á. Furka, T. Szell: Decomposition of nitro compounds in the presence of aluminium chloride, In: Acta Phys. et Chem. Szeged, Vol. 7, 1961: 129.
J. Egyed, Á. Furka, T. Szell: Fries rearrangement of 3-nitrophenyl-3-nitrobenzoate, In:
Acta Phys. et Chem. Szeged, Vol. 11, 1965: 51.
Á. Furka, L. B. Smillie, K. J. Stevenson, C. O. Parkes: Amino acid sequence of chymotrypsinogen B, In: Fed. Proc., Vol. 25, 1966: 789.
L. B. Smillie, Á. Furka, N. Nagabhushan, K. J. Stevenson, C. O. Parkes: Structure of chymotrypsinogen B compared with chymotrypsinogen A and trypsinogen, In: Nature, Vol. 218, 1968: 343.
Á. Furka, F. Sebestyén: Enhancement of the solubility of S-alkylated proteins by carboxyl group modification, In: FEBS Letters, Vol. 4, 1969: 207.
Á. Furka, F. Sebestyén: Fractionation of crystallized ovalbumin on DEAE-cellulose, In: Acta Biochim. et Biophys. Acad. Sci. Hung., Vol. 4, 1969: 379.
Á. Furka, F. Sebestyén, T. Karácsonyi: New method for isolation of the C-terminal fragment of peptides and proteins, In: FEBS Letters, Vol. 6, 1970: 34.
Á. Furka, F. Sebestyén: Studies on carboxyl modified proteins and their enzymatic hydrolyzates, In: Acta Biochim. et Biophys. Acad. Sci. Hung., Vol. 5, 1970: 131.
Á. Furka: Group separation: A new method facilitating isolation of peptides from digests of high molecular weight proteins, In: Acta Biochim. et Biophys. Acad. Sci. Hung., Vol. 6, 1971: 153.
Á. Furka, F. Sebestyén: Do the C-H bonds contribute to the stabilization energy of benzene?, In: Croatica Chem. Acta, Vol. 53, 1980: 555-559.
Á. Furka, F. Sebestyén, L. Feuer, A.. Horváth, J. Hercsel, S. Ormai, B. Bányai:Isolation of g-L-glutamyl-taurine from the protein free extract of bovine parathyroid powder, In: Acta Biochim. Biophis. Acad. Sci. Hung., Vol. 15, 1980: 39-47.
F. Sebestyén, Á. Furka, L. Feuer, J. Gulyás, Gy. Szókan: Synthesis of g-L-glutamyl-taurine, In: Int. J. Peptide Protein Res., Vol. 16, 1980: 245-247.
J. Gulyas, F. Sebestyén, Á. Furka, L. Feuer, G. Dibó: Synthesis of g-glutamyl and d-aminoadipyl derivatives of some aminoalkanesulfonic acids, In: Ann. Univ. Sci. Budapest. Lorando Eotvos Nominatae, Sect. Chim., Vol. 16, 1980: 41-46.
Á. Furka: The carbon-carbon bond energy, In: Ann. Univ. Sci. Budapest. Lorando Eotvos Nominatae, Sect. Chim., Vol. 16, 1980: 35-40.
Á. Furka, G. Dibó, J. Kovács, F. Sebestyén: An improved method for isolation of the C-terminal fragment of proteins, In: Anal. Biochem., Vol. 129, 1983: 14-21.
Á. Furka: Comparison of the heats of formation of hydrocarbons, In: Croatica Chem. Acta, Vol. 56, 1983: 199-201.
Á. Furka: An empirical formula expressing the mutual dependence of C-C bond distances, Croatica Chem. Acta, Vol. 56, 1983: 191-197.
J. Gulyás, A. Horváth, Á. Furka, F. Sebestyén, L. Feuer: Synthetic derivatives and analogues of g-L-glutamyl-taurine, a bioactive compound from bovine parathyroids., In: Int. J. Peptide Protein Res., Vol. 24, 1984: 367-376.
G. Dibó, Á. Furka, F. Sebestyén, A. Fehérvári: Isolation of the C-terminal fragment of proteins after re-digestion of their esterified tryptic hydrolyzates, In: Int. J. Peptide Protein Res., Vol. 27, 1986: 355-359.
J. Gulyas, F. Sebestyén, J. Hercsel-Szepespataky, Á. Furka: An improved synthesis of g-L-glutamyl-taurine, In: Org. Prep. Proced. Int., Vol. 19, 1987: 64-66.
Á. Furka, F. Sebestyén, M. Asgedom, G. Dibó: Cornucopia of peptides by synthesis In: Highlights of Modern Biochemistry, Proceedings of the 14th International Congress of Biochemistry, VSP. Utrecht, The Netherland, 1988, Vol. 5: 47.
Á. Furka, F. Sebestyén, M. Asgedom, G. Dibó: More peptides by less labour, In: Abstr. 10th Int. Symp. Med. Chem., Budapest, Hungary, 1988: 288.
Á. Furka, F. Sebestyén, J. Gulyás: Computer made electrophoretic peptide maps, In: Proc. 2nd Int. Conf. Biochem. Separations, Keszthely, Hungary, 1988: 35-42.
Á. Furka, F. Sebestyén, M. Asgedom, G. Dibó: General method for rapid synthesis of multicomponent peptide mixtures, In: Int. J. Peptide Protein Res., Vol. 37, 1991: 487-493.
F. Sebestyén, G. Dibó, A. Kovács, Á. Furka: Chemical synthesis of peptide libraries, In: Bioorg. & Med. Chem. Letters, Vol. 3, 1993: 413-418.
F. Sebestyén, G. Dibó, Á. Furka: Efficiency and limitations of the "portioning-mixing" peptide synthesis, In: C. H. Schneider, A. N. Eberle (Eds.) Peptides 1992 (Proceedings of the 22nd European Peptide Symposium), ESCOM Leiden, 1993: 63-64.
Á. Furka, F. Sebestyén, G. Dibó: Computer program facilitating separation of peptides from mixtures prepared by the "portioning-mixing" method, In: C. H. Schneider, A. N. Eberle (Eds.) Peptides 1992 (Proceedings of the 22nd European Peptide Symposium), ESCOM Leiden, 1993: 463-464.
Á. Furka, I. Czimer: New thermochemical reference system expressing the relative energy of organic compounds, In: Structural Chemistry, Vol. 4, 1993: 327-331.
F. Sebestyén, G. Dibó, Á Furka: Portioning-mixing: A multi-purpose technique in peptide synthesis, In: N. Yanaihara (Ed.) Peptide Chemistry 1992 (proceedings of the 2nd Japan Symposium on Peptide Chemistry) ESCOM Leiden, 1993: 84-86.
G. Dibó, F. Sebestyén, L. Urge, M. Hollósi, Zs. Mayer, A. Kovacs and Á. Furka:Synthesis of glycopeptide mixtures by the 'portioning-mixing' method, In N. Yanaihara (Ed.) Peptide Chemistry 1992 (proceedings of the 2nd Japan Symposium on Peptide Chemistry) ESCOM Leiden, 1993: 70-71.
Á. Furka, F. Sebestyén, E. Campian: The use of sub-library kits in a new screening strategy, In: R. S. Hodges, J. A. Smith (Eds) Peptides. Chemistry, Structure and Biology, Proc. 13th American Peptide Symp. ESCOM, Leiden, 1994: 986-988.
Á. Furka, F. Sebestyén, E. Campian: Peptide sub-library kits, In: R. Epton, (Ed.) Innovation and perspectives in solid phase synthesis, Peptides, Proteins and Nucleic Acids 1994. Mayflower Worldwide Limited, Birmingham, 1994: 385-390.
E. Campian, F. Sebestyén, Á. Furka: Colored and fluorescent solid supports
In: R. Epton, (Ed.) Innovation and perspectives in solid phase synthesis. Peptides, Proteins and Nucleic Acids 1994. Mayflower Worldwide Limited, Birmingham, 1994: 469-472.
Á. Furka: Sub-Library Composition of Peptide Libraries. Potential Application in Screenin, In: Drug Development Research Vol. 33, 1994: 90-97.
E. Campian, F. Sebestyén, F. Major and Á. Furka: Synthesis of Support-bound Peptides Carrying Color Labels, In: Drug Development Research Vol. 33, 1994: 98-101.
F. Sebestyén, T. Szalatnyai, J. A. Durgo, Á. Furka: Binary Synthesis of Multicomponent Peptide Mixtures by the Portioning-mixing Technique, In: J. Peptide Sci., Vol. 1, 1994: 26-30.
Á. Furka, F. Sebestyén: Composition of biooligomer libraries: Potential application in screening, In: H. L. S. Maia (Ed.) Peptides 1994 (Proceedings of the 23rd European Peptide Symposium), ESCOM Leiden, 1995: 498-499.
Á. Furka: History of combinatorial chemistry, In: Drug Development Research, Vol. 36, 1995: 1-12.
Á. Furka, E. Campian, M. L. Peterson, H. H. Saneii: Applicability of omission libraries in screening, In: P. T. P. Kaumaya, R. S. Hodges (Eds.) Peptides. Chemistry, Structure and Biology (Proceedings of the 14th American Peptide Symposium) Mayflower Scientific Ltd. England, 1996: 317-318.
F. Sebestyén, K Kindla, W. Rapp, E. Campian, Á. Furka: Synthesis of colored peptide libraries, In: P. T. P. Kaumaya, R. S. Hodges (Eds.) Peptides. Chemistry, Structure and Biology (Proceedings of the 14th American Peptide Symposium) Mayflower Scientific Ltd. England, 1996: 319-320.
F. Sebestyén, A. Kovács, W. Rapp, E. Campian, Á. Furka: Synthesis of genetic peptide libraries, In: P. T. P. Kaumaya, R. S. Hodges (Eds.) Peptides. Chemistry, Structure and Biology (Proceedings of the 14th American Peptide Symposium) Mayflower Scientific Ltd. England, 1996: 321-322.
Á. Furka, S. R. Wilson and A. W. Czarnik (Editors): Combinatorial Chemistry Synthesis and Application (Book review), In: The Chemical Intelligencer, 1998: 61-62.
Á. Furka: How to prepare a cornucopia of new substances?, In: Leonardo, Vol. 31, 1998: 42-43.
F. Sebestyén, Gy. Szendrei, M. Mak, M. Doda, E. Illyés, Gy. Szókán, K. Kindla, W. Rapp, P. Szego, E. Campian, Á. Furka: Coloured Peptides: Synthesis, Properties and Use in Preparation of Sub-Library Kits, In: J. Peptide Sci., Vol. 4, 1998: 294-299.
E Câmpian, J. Chou, M. L. Peterson, H. H. Saneii and Á. Furka: Synthesis and Applicability of Monomer Tester Mixtures, In: R. Ramage, R. Epton (Eds.) Peptides 1996 (Proceedings of the 24th European Peptide Symposium Edinburgh, 1996) Mayflower Scientific Ltd. England, 1998: 131-134.
E. Câmpian, M. L. Peterson, H. H. Saneii and Á. Furka: Automated Synthesis in a Single Process of Nine First Order Sub-libraries Of an Amino Acid Occurrence Library, In: R. Ramage, R. Epton (Eds.) Peptides 1996 (Proceedings of the 24th European Peptide Symposium Edinburgh, 1996) Mayflower Scientific Ltd. England, 1998: 285-286.
F. Sebestyén, Gy. Szendrei, M. Mak, M. Doda, E. Ilyes, Gy. Szókán, K. Kindla, W. Rapp, P. Szego, E. Campian and Á. Furka: Coloured Peptides: Synthesis and Use in Preparation of Peptide Sub-library Kits, In: J. Peptide Sci., Vol. 4, 1998: 294-299.
E. Câmpian, M. Peterson, H. H. Saneii, Á. Furka: Deconvolution by Omission Libraries Bioorg. & Med. Chem. Letters 8, 1998: 2357-2362.
Á. Furka: The Portioning-mixing (split) Method, In:BIOforum International, Vol. 2, 1998: 169-172.
Á. Furka: Combinatorial Chemistry, In: The Chemical Intelligencer, 1999: 22-27.
Á. Furka, E. Câmpian, H. R. Tanner, H. H. Saneii: Determination of the amino acid composition of bioactive components of peptide libraries, In: J. P. Tam, P. T. P. Kaumaya (Eds) Peptides. Frontiers of Peptide Science, Proceedings of the 15th American peptide Symposium, Nashville, Klauver Academic Publishers, Dodrecht/Boston/London, 1999: 34-36.
Á. Furka, & Bennett, W.D. : Combinatorial libraries by portioning and mixing, In: Comb. Chem. High Throughput Screening, Vol. 2, 1999: 105-122.
Á. Furka: Ten Years of the Portioning-Mixing (Split) Synthesis of Combinatorial Libraries, In: S Bajusz and F. Hudecz (Eds) Peptides 1998, Proceedings of the Twenty-Fifth European Peptide Symposium, Budapest, Akadémiai Kiadó, 1999: 60-61.
Á. Furka, J. W. Christensen, E. H. Hans, R. Tanner, H. Saneii: The string synthesis. A spatially addressable split procedure, In: J. Comb. Chem., Vol. 2, 2000: 220-223.
Á. Furka: Redistribution in Combinatorial Synthesis. A Theoretical Approach, In: Combinatorial Chemistry & High Throughput Screening,Vol. 3, 2000: 197-209.
Á. Furka: Combinatorial chemistry: 20 years on ..., In: Drug Discovery Today, Vol. 7, 2002: 1-4.
